GHK-Cu
Glycyl-L-Histidyl-L-Lysine Copper Complex
A naturally occurring copper peptide found in human plasma, saliva, and urine. Declines significantly with age. Known for tissue repair, skin regeneration, and anti-aging properties.
Typical Cost
$25-60/vial (50mg)
Status
Research
Peptide Profile
GHK-Cu
Mechanism of Action
Modulates gene expression related to tissue repair, stimulates collagen and elastin production, enhances antioxidant defense, and promotes blood vessel growth. Copper ion enables cellular signaling for regeneration.
Common Dosages
subcutaneous
1-2mg
Daily · 4-6 weeks
topical
2-5% serum
1-2x daily · Ongoing
Benefits
Improved skin elasticity
Reduced wrinkles
Enhanced wound healing
Hair growth stimulation
Tissue repair
Anti-inflammatory effects
DNA repair support
Side Effects
Skin irritation (topical)
Headache (rare)
Nausea (rare injectable)
Metallic taste (rare)
Key Research
GHK-Cu and skin regeneration
Demonstrated significant improvement in skin elasticity, density, and wrinkle reduction in clinical studies
GHK peptide as a natural modulator of gene expression
Identified as a regulator of multiple genes involved in tissue repair and anti-aging pathways
Regulatory Status
Cosmetic ingredient status. Available in skincare products. Injectable forms considered research compounds. FDA has not approved for therapeutic use.
Contraindications
- ⚠Copper metabolism disorders
- ⚠Wilson's disease
- ⚠Pregnancy/breastfeeding
For GLP-1 users concerned about 'Ozempic face' or skin changes during weight loss, GHK-Cu's collagen-stimulating properties complement SeraVia's beauty-from-within approach.
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