What should I do if I experience diarrhea while taking GLP-1 medications?

Diarrhea is a common GI side effect of GLP-1 medications, occurring in approximately 15-25% of users. It results from the medication's effect on gut motility and fluid balance. Most cases are mild to moderate and resolve within a few weeks as your body adapts.

To manage diarrhea, stay well-hydrated with water, clear broths, or oral rehydration solutions. Temporarily avoid dairy products, high-fiber foods, caffeine, and artificial sweeteners, which can worsen symptoms. The BRAT diet (bananas, rice, applesauce, toast) can be helpful during acute episodes. If diarrhea persists beyond 2 weeks, is severe, or is accompanied by blood, fever, or severe abdominal pain, contact your healthcare provider to rule out other causes and discuss management options.