What are the symptoms of pancreatitis and when should I seek emergency care?

Pancreatitis (inflammation of the pancreas) is a serious potential side effect of GLP-1 medications. Seek immediate emergency care if you experience: severe, persistent abdominal pain that may radiate to your back, severe nausea and vomiting, fever, rapid heartbeat, or abdominal tenderness/swelling. The pain is often described as severe, constant, and located in the upper abdomen. Pancreatitis can be life-threatening and requires immediate medical attention. While GLP-1s have been associated with pancreatitis in some cases, it's relatively rare. The risk may be higher in patients with a history of gallstones, heavy alcohol use, very high triglycerides, or previous pancreatitis. If you develop these symptoms while on GLP-1 therapy, the medication should be discontinued and not restarted. Your doctor will perform blood tests (lipase and amylase levels) and imaging to diagnose pancreatitis. Hospitalization is often required for pain management, IV fluids, and monitoring.