How can I prevent muscle loss while losing weight on GLP-1s?

Preventing muscle loss during GLP-1 therapy requires intentional effort. Aim for 0.7-1.0 grams of protein per pound of goal body weight daily. Resistance training 3-4 times weekly is essential - focus on compound movements (squats, deadlifts, presses). Prioritize sleep (7-9 hours) as muscle protein synthesis occurs during rest. Don't reduce calories too aggressively - aim for 500-750 calorie deficit maximum. Consider working with a trainer experienced in weight loss transitions. Some patients add creatine monohydrate (5g daily) to support muscle preservation. SeraVia Muscle+ Protect provides targeted amino acid support specifically designed for GLP-1 users concerned about maintaining lean mass during rapid weight loss. Blood tests tracking muscle mass or strength benchmarks help monitor progress beyond just scale weight.